When a lifesaving drug — insulin — is used as a homicide weapon, medical professionals are probably unprepared to contemplate that the difficult-to-detect remedy was used to commit a criminal offense, in response to a forensic pathologist who labored on the recent case of a West Virginia pharmacist convicted of fatally dosing her husband.
Dr. Paul Uribe, a former navy medical expert who consults as a pathologist throughout the US and helped remedy a string of insulin murders at a West Virginia veterans hospital, instructed NBC Information that there seem like few protocols displaying pathologists and emergency room medical doctors how you can finest deal with the instances.
“You’re not going to stumble throughout an insulin murder,” Uribe mentioned. “It’s a must to have a suspect and you must search for it, as a result of for those who’re not on the lookout for it, you’re not going to search out it.”
Whereas such crimes are uncommon, Uribe mentioned, some latest instances within the U.S. have had a staggering variety of victims. In Pennsylvania, a nurse confessed to trying to kill 19 people with insulin at 5 amenities between 2020 and 2023. Seventeen of her sufferers died. On the West Virginia veterans hospital, a nurse admitted in 2021 to killing seven aged sufferers with insulin.
Uribe mentioned he is aware of of no protocols promoted by organizations for ER medical doctors or health workers and is aware of of just one state — West Virginia — the place lawmakers have sought to reckon with this obvious lack of know-how. A bill introduced this year within the state Legislature seeks to require emergency rooms to check sufferers for insulin once they’re admitted with doable signs of insulin poisoning.
Jonathan Jones, the previous president of the American Academy of Emergency Medication, mentioned that whereas the group is anxious about insulin overdoses, it doesn’t imagine in “legislating medical care.”
“The very best medical care is offered by correctly educated, skilled and board-certified physicians and never by legislators,” he mentioned in an electronic mail to NBC Information. “We imagine in persevering with medical schooling round this challenge and all others relevant to the doctor’s specialty however oppose remedy mandates and repercussions.”
He didn’t reply to a request for remark about whether or not ERs want stronger tips.
Requested if forensic pathologists want higher protocols, Reade Quinton, president of the Nationwide Affiliation of Medical Examiners, mentioned: “I’m not certain that’s the proper query. What health workers want is unobstructed entry to scene info, witness statements and medical data so we will carry out a whole and impartial loss of life investigation.”

The lead sponsor of the West Virginia invoice didn’t reply to requests for remark. However the mother and father of Michael Cochran — who was killed by his pharmacist spouse and for whom the invoice is known as — imagine the laws may function a mannequin for the nation. And it may assist others keep away from the gut-wrenching seek for solutions that they endured for years.
“They received’t have to attend for a end result like we needed to wait,” Cochran’s mom, Donna Bolt, instructed “Dateline.” “Six years.”
Seven lifeless sufferers at VA hospital
Uribe’s first insulin murder case was on the veterans hospital in Clarksburg, West Virginia. Then a pathologist with the Armed Forces Medical Examiner System, Uribe mentioned he was requested in late 2018 to look at a sequence of mysterious deaths amongst aged sufferers, all of whom had been discovered to have had extreme hypoglycemia, or low blood sugar.
The situation will be attributable to excessively excessive doses of insulin, which acts as a lifesaving regulator of blood sugar for folks with diabetes.
Among the veterans had been diabetic, Uribe recalled, however others weren’t. He mentioned he was requested to discover a “smoking gun” that would show insulin was the homicide weapon.
For emergency room physicians and pathologists, he mentioned, this is usually a tough job due to how shortly the physique metabolizes insulin. The take a look at cited within the West Virginia laws — often called a “c-peptide” take a look at — can measure insulin, Uribe mentioned, however timing is essential: It needs to be performed earlier than medical doctors present remedy for low blood sugar, he mentioned.
“As a result of when you give that individual glucose, that triggers the physique’s pure launch of insulin, and it’ll throw off the insulin c-peptide measure,” he mentioned.
Many smaller hospitals usually don’t have the exams obtainable, he added.
Uribe cited two doable strategies for pathologists to doc insulin. Probably the most widespread methods of administering the remedy is thru an injection, and it could possibly briefly linger within the physique’s tissue at an injection website, he mentioned. Researchers have additionally documented insulin in postmortem vitreous fluid, a substance discovered within the eyeball, he mentioned.
In West Virginia, the our bodies of seven veterans had been exhumed and Uribe examined injection website tissue samples, he mentioned. The exams revealed hint quantities of insulin in a number of the victims, together with those that weren’t diabetic and had by no means been prescribed the remedy, he mentioned.
“That was the definitive proof that they had been injected with insulin,” he mentioned.

Reta Mays, a nursing assistant on the hospital, was finally recognized as a suspect within the killings. She admitted to administering the deadly doses, pleading responsible to seven counts of second-degree homicide and one depend of assault with intent to commit homicide in reference to the loss of life of an eighth man. Mays was sentenced to seven life sentences.
A deadly dose from a pharmacist
In Uribe’s second case, pharmacist Natalie Cochran was convicted in January of giving her husband a deadly dose of the drug in a plot that prosecutors mentioned was geared toward protecting up a multimillion-dollar fraud that she perpetrated on family and friends.
Nevertheless it took years for the case to be resolved.
In February 2019, Michael Cochran was hospitalized in an unresponsive state earlier than he was faraway from a ventilator and positioned in hospice. He was 38. His loss of life certificates listed his method of loss of life as “pure.”

Michael Cochran’s emergency room data confirmed that when he was admitted to the hospital, his blood sugar had plummeted, although he had no historical past of diabetes, Uribe mentioned. No insulin take a look at was performed on the time, he mentioned.
However Tim Bledsoe, a detective with the West Virginia State Police, got here to suspect that Natalie Cochran might have performed a job in her husband’s loss of life, and through a search of her dwelling, he found {a partially} used vial of insulin in her fridge.
Figuring out that nobody within the dwelling was diabetic, he requested Natalie Cochran in regards to the vial, Bledsoe instructed “Dateline.” She instructed the detective she saved it there for a neighbor’s diabetic son, Bledsoe mentioned. However the neighbor, Jennifer Davis, denied this and instructed “Dateline” that Natalie Cochran mentioned she’d requested for the insulin for herself, claiming that she was utilizing it to recuperate from a most cancers prognosis that prosecutors later mentioned she faked.
She requested for the insulin the morning Michael Cochran first grew to become sick, Davis mentioned.
Two years after Michael Cochran’s loss of life, his spouse was indicted on a homicide cost. An post-mortem had been carried out seven months after his loss of life, however by then his physique was in a complicated state of decomposition and the medical expert dominated his reason behind loss of life undetermined, Bledsoe mentioned.
It isn’t clear why an post-mortem was not performed instantly after his loss of life, neither is it clear if any steps had been taken within the examination to try to doc postmortem insulin. The West Virginia Division of Well being and Human Assets, which oversees the state medical expert, didn’t reply to a request for remark.
Uribe mentioned it’s unlikely any postmortem proof of insulin may have been discovered given how a lot time handed between when Michael Cochran would have been given the drug and when he died.
The undetermined discovering, mixed with a scarcity of bodily proof, led the Raleigh County district lawyer to drop the case, in response to the county’s present prime prosecutor, Tom Truman.
“In case you don’t have the medical expert saying murder, you’ve obtained a giant drawback,” he instructed “Dateline.”
One other exhumation — after which a conviction
However two years later, the cost was refiled after Uribe was requested to look at the case. Throughout a second exhumation and post-mortem, Uribe mentioned that he looked for doable injection websites however that Michael Cochran’s stays had been skeletal by that time and the examination yielded nothing.
Nonetheless, Uribe mentioned no different motive that would clarify Michael Cochran’s plummeting blood sugar — equivalent to sepsis or a rampant an infection — had been documented in his medical data. Mixed with different circumstances surrounding Michael Cochran’s loss of life, Uribe dominated the loss of life an insulin murder.
At trial, an endocrinologist who testified for the prosecution agreed that no different rationalization may account for Michael Cochran’s hypoglycemia.

Natalie Cochran’s attorneys acknowledged that she defrauded associates and relations — she’d pleaded responsible in a separate federal fraud and cash laundering case — however they mentioned she had nothing to do with her husband’s loss of life, which they attributed to a deadly mixture of exercise dietary supplements, steroids and presumably his personal use of insulin.
On Jan. 29, after two hours of deliberation, a jury convicted Natalie Cochran of first-degree homicide. She was sentenced to life with out the opportunity of parole.
To Uribe, this case and the killings on the veteran’s hospital underscore the necessity for higher insulin overdose tips.
For physicians, he mentioned, these protocols may embody watching out for purple flags like severely low, unexplained blood sugar in a nondiabetic individual, or unexplained low potassium, often called hypokalemia, which will also be deadly and attributable to extreme insulin.
And so they want to make sure that they administer a c-peptide take a look at earlier than remedy, he mentioned.
Pathologists ought to seek for doable injection websites, he mentioned, and they need to strive testing vitreous fluid, he mentioned.
“In case you’re capable of detect that within the vitreous fluid of somebody who’s not a diabetic, who’s by no means been prescribed this remedy and has no historical past of them being injected, that would legitimately let you know one thing,” he mentioned.