Newswise — LOS ANGELES, July 15, 2025 — Researchers at Vanderbilt College, Johns Hopkins College, College of Miami, and The Alfred Hospital studied the lungs of topics together with Veterans utilizing expertise developed by 4DMedical known as X-ray Velocimetry Lung Air flow Evaluation Software program (XV LVAS®). Findings of the most important, multi-center examine had been described within the article, “X-ray velocimetry provides temporally and spatially-resolved biomarkers of lung ventilation in small airways disease” printed within the journal Respiratory Analysis and confirmed that 4DMedical’s distinctive lung imaging expertise—XV LVAS— can detect early or refined small airway illness sometimes undiagnosed with standard testing.
“We’re now in a position to see the invisible,” says Dr. Bradley Richmond, a pulmonologist who together with Dr. Michael Lester co-led the examine. “XV LVAS expertise offers us a window into components of the lung we have by no means been in a position to assess so exactly earlier than. It might remodel look after sufferers whose signs had been beforehand a thriller.”
For many years, docs have relied on respiratory checks resembling spirometry and CT scans to evaluate lung well being. Nonetheless, some situations—notably these impacting the smallest airways—typically go undetected, leaving sufferers with out clear diagnoses or efficient remedy. Now, with 4DMedical’s XV LVAS expertise, clinicians can securely add fluoroscopy scans for superior evaluation. This progressive system produces detailed, real-time shade maps that present how air flows by way of totally different lung areas as sufferers breathe. The outcomes are delivered in clear, easy-to-read stories that combine into present scientific workflows.
XV LVAS supplies clinicians with extra useful lung element than ever earlier than—spatially resolved, actionable data for extra optimized prognosis and remedy choices. Utilizing quick, low-dose fluoroscopy XV LVAS affords a validated leap ahead in lung diagnostics.
The examine revealed a number of vital insights. The XV evaluation detected lung issues in sufferers—together with fight veterans—even when customary respiratory checks and CT scans indicated regular lung operate. The expertise additionally uncovered distinctive patterns linked to the early levels of power obstructive pulmonary illness (COPD), a situation affecting greater than 15 million Individuals. Moreover, with its easy, low-radiation scan, XV LVAS permits sufferers to probably keep away from extra invasive procedures, resembling biopsies, whereas offering solutions beforehand inaccessible with different strategies.
Now, clinicians can detect illness invisible to spirometry, scale back pointless invasive testing, and supply personalised respiratory care—all supported by peer-reviewed analysis. XV LVAS could make a distinction for thousands and thousands of individuals coping with unexplained shortness of breath, together with army veterans, COPD sufferers, and others affected by hidden types of lung illness. Already cleared for scientific use in the US and Australia, this progressive lung scan is now being studied in bigger affected person teams.
About 4DMedical
4DMedical is a world medical expertise firm on the forefront of creating instruments for cardiopulmonary diagnostics. The corporate delivers a complicated suite of software program imaging options that present clinicians with complete, non-invasive insights into lung and coronary heart operate. 4DMedical’s SaaS-based applied sciences allow the visualization and quantification of regional lung air flow and different important metrics, all utilizing present imaging tools and low-dose scans. 4D is headquartered in Melbourne, Australia with U.S. places of work in Los Angeles, California.
