Aliza Naaz, the two-year-old toddler, after Bone Marrow Transplant in SCB Medical Faculty Hospital, Cuttack.
| Picture Credit score: Particular Association
A four-year-old woman has donated her stem cells to her two-year-old sister, who’s battling acute myeloid leukemia (AML), a extreme type of blood most cancers. This marks the first-ever allogeneic bone marrow transplant (BMT) carried out on such a younger youngster in Odisha.
Based on the BMT unit of SCB Medical Faculty Hospital (SCBMCH), the place the process was carried out, Aliza Naaz, the two-year-old daughter of Sharukh Ansari from Jharkhand’s Dhanbad was recognized with high-risk AML. She initially underwent induction chemotherapy on the Tata Memorial Hospital (TMH) in Jamshedpur in July 2024.
“Submit-chemotherapy analysis revealed that the illness persevered, upgrading her situation to a high-risk class,” Professor R.Okay. Jena, a famend BMT doctor, mentioned.
“She subsequently obtained additional chemotherapy in October 2024. Given the severity of her case, medical doctors advisable an allogeneic BMT. Human leukocyte antigen matching carried out at TMH confirmed a 100% match together with her elder sister, who’s simply 4 years outdated,” Prof. Jena mentioned.
She was referred to the next centre with a budgetary expenditure of ₹30 lakhs as BMT services at TMH, Jamshedpur, didn’t exist.
“Because the mother and father of the affected person expressed their incapability to bear such an enormous value, the TMH medical doctors referred their case to the BMT unit of SCBMCH, Cuttack, the place such services are supplied freed from value,” Sudha Sethy, Head of Medical Hematology division of SCBMCH, mentioned.
The BMT unit of SCBMCH evaluated Aliza, who was admitted on January 7. Furthermore, her mother and father have been counselled relating to penalties of the process. One BMT crew was constituted with two colleges from paediatric division. The preparation started from eleventh day of admission on January 27. In the meantime, Aliza’s sister Aatifa was admitted on January 28. The stem cell assortment was very difficult since this was the primary case the place the stem cell donor is so younger.
“The identical blood group was matched and used to prime the aphaeresis system because the youngster’s blood quantity is just too low to maintain the dynamics of stem cell assortment. After priming, stem cell aphaeresis began from 9 a.m. on February 6 and accomplished at 1 p.m. the identical day,” Dr. Sethy mentioned. Subsequently, stem cell administration was finished efficiently on February 7.
Medical doctors finishing up the put up BMT observe up mentioned the affected person had an infection and chemotherapy induced mucositis which was managed with antibiotics and different supportive measures. The kid was secure with no fever at the same time as biochemical and haematological parameters have been inside regular limits as per the expectation.
“This landmark BMT will create alternative for treatment of many youngsters with blood and different ailments like Thalassemia, Sickle Cell Illness, Aplastic Anaemia, numerous blood most cancers, different cancers, and associated ailments. These ailments taken collectively are big in numbers, and represent a major socio-economic burden on our State. 1000’s of sufferers in our State want this process and will not be in a position to obtain as a result of many logistic challenges outdoors,” Prof. Jena mentioned.
Inaugurated in 2014, the BMT unit in SCBMCH was the primary such facility in a authorities hospital in the whole nation. The identical process, which might value round ₹15-30 lakhs and requires a ready interval of not less than one 12 months outdoors Odisha, is carried out freed from value right here. Up to now 11 years, as many as 176 BMT procedures have been efficiently accomplished with greater than 80% in restoration.
Revealed – February 19, 2025 09:52 pm IST
