Correction to. Minimal info for research of extracellular vesicles (MISEV2023): From primary to superior approaches, J Extracell Vesicles 13(5) (2024) e12451. https://doi.org/10.1002/jev2.12451
van Niel G, et al. Shedding mild on the cell biology of extracellular vesicles. Nat Rev Mol Cell Biol. 2018;19(4):213–28. https://doi.org/10.1038/nrm.2017.125.
He B, et al. RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles. Nat Crops. 2021;7(3):342–52. https://doi.org/10.1038/s41477-021-00863-8.
Zhang S, et al. Intestine-liver axis: potential mechanisms of motion of food-derived extracellular vesicles. J Extracell Vesicles. 2024;13(6):e12466. https://doi.org/10.1002/jev2.12466.
Alvarez-Erviti L, et al. Supply of siRNA to the mouse mind by systemic injection of focused exosomes. Nat Biotechnol. 2011;29(4):341–5. https://doi.org/10.1038/nbt.1807.
Alzahrani FA, et al. Plant-derived extracellular vesicles and their thrilling potential as the way forward for Subsequent-Era Drug Supply. Biomolecules. 2023;13(5). https://doi.org/10.3390/biom13050839.
Halperin W, Jensen WA. Ultrastructural adjustments throughout development and embryogenesis in carrot cell cultures. J Ultrastruct Res. 1967;18(3):428–43. https://doi.org/10.1016/s0022-5320(67)80128-x.
Regente M, et al. Vesicular fractions of sunflower apoplastic fluids are related to potential exosome marker proteins. FEBS Lett. 2009;583(20):3363–6. https://doi.org/10.1016/j.febslet.2009.09.041.
Liu X, et al. Unlocking the Medicinal potential of plant-derived extracellular vesicles: present progress and future views. Int J Nanomed. 2024;19:4877–92. https://doi.org/10.2147/ijn.S463145.
Ren JL, et al. Efficacy analysis, lively substances, and multitarget exploration of natural medication. Tendencies Endocrinol Metab. 2023;34(3):146–57. https://doi.org/10.1016/j.tem.2023.01.005.
Zhao Q, et al. Consensus assertion on analysis and software of Chinese language natural medication derived extracellular vesicles-like particles (2023 version). Chin Herb Med. 2024;16(1):3–12. https://doi.org/10.1016/j.chmed.2023.11.002.
Lai W, et al. Zingiber officinale: a scientific evaluate of Botany, Phytochemistry and Pharmacology of Intestine Microbiota-related gastrointestinal advantages. Am J Chin Med. 2022;50(4):1007–42. https://doi.org/10.1142/s0192415x22500410.
Zhu H, He W. Ginger: a consultant materials of herb-derived exosome-like nanoparticles. Entrance Nutr. 2023;10:1223349. https://doi.org/10.3389/fnut.2023.1223349.
Mao X, et al. Advances within the research of plant-derived extracellular vesicles within the skeletal muscle system. Pharmacol Res. 2024;204:107202. https://doi.org/10.1016/j.phrs.2024.107202.
Feng J, et al. Plant-Derived Vesicle-Like nanoparticles as Promising Biotherapeutic Instruments: Current and Future. Adv Mater. 2023;35(24):e2207826. https://doi.org/10.1002/adma.202207826.
Li A, et al. Plant-derived nanovesicles: additional exploration of biomedical operate and software potential. Acta Pharm Sin B. 2023;13(8):3300–20. https://doi.org/10.1016/j.apsb.2022.12.022.
Yang LY, et al. Rising drug supply vectors: Engineering of Plant-Derived nanovesicles and their purposes in Biomedicine. Int J Nanomed. 2024;19:2591–610. https://doi.org/10.2147/ijn.S454794.
He B, et al. Plant extracellular vesicles: Trojan horses of cross-kingdom warfare. FASEB Bioadv. 2021;3(9):657–64. https://doi.org/10.1096/fba.2021-00040.
Ly NP, et al. Plant-derived nanovesicles: present understanding and purposes for most cancers remedy. Bioact Mater. 2023;22:365–83. https://doi.org/10.1016/j.bioactmat.2022.10.005.
Cui Y, et al. Plant extracellular vesicles. Protoplasma. 2020;257(1):3–12. https://doi.org/10.1007/s00709-019-01435-6.
Mu N, et al. Plant-Derived Exosome-Like nanovesicles: present progress and prospects. Int J Nanomed. 2023;18:4987–5009. https://doi.org/10.2147/ijn.S420748.
Li X, et al. Biogenesis and performance of Multivesicular our bodies in Plant Immunity. Entrance Plant Sci. 2018;9:979. https://doi.org/10.3389/fpls.2018.00979.
Kalluri R, LeBleu VS. The biology, operate, and biomedical purposes of exosomes. Science. 2020;367(6478). https://doi.org/10.1126/science.aau6977.
Jadli AS, et al. Inside(sight) of tiny communicator: exosome biogenesis, secretion, and uptake. Mol Cell Biochem. 2020;467(1–2):77–94. https://doi.org/10.1007/s11010-020-03703-z.
An Q, et al. Multivesicular our bodies take part in a cell wall-associated defence response in barley leaves attacked by the pathogenic powdery mildew fungus. Cell Microbiol. 2006;8(6):1009–19. https://doi.org/10.1111/j.1462-5822.2006.00683.x.
Wang J, et al. An exocyst-positive organelle distinct from multivesicular endosomes and autophagosomes, mediates cytosol to cell wall exocytosis in Arabidopsis and tobacco cells. Plant Cell. 2010;22(12):4009–30. https://doi.org/10.1105/tpc.110.080697.
Wang X, et al. Protein secretion in crops: standard and unconventional pathways and new methods. J Exp Bot. 2017;69(1):21–37. https://doi.org/10.1093/jxb/erx262.
Cui Y, et al. A complete-cell electron tomography mannequin of vacuole biogenesis in Arabidopsis root cells. Nat Crops. 2019;5(1):95–105. https://doi.org/10.1038/s41477-018-0328-1.
Doyle LM, Wang MZ. Overview of Extracellular vesicles, their origin, composition, function, and strategies for Exosome isolation and evaluation. Cells. 2019;8(7). https://doi.org/10.3390/cells8070727.
Manjithaya R, Subramani S. Position of autophagy in unconventional protein secretion. Autophagy. 2010;6(5):650–1. https://doi.org/10.4161/auto.6.5.12066.
Movahed N, et al. Turnip Mosaic Virus Elements are launched into the Extracellular area by vesicles in contaminated leaves. Plant Physiol. 2019;180(3):1375–88. https://doi.org/10.1104/pp.19.00381.
An Q, et al. Multivesicular compartments proliferate in vulnerable and resistant MLA12-barley leaves in response to an infection by the biotrophic powdery mildew fungus. New Phytol. 2006;172(3):563–76. https://doi.org/10.1111/j.1469-8137.2006.01844.x.
Regente M, et al. Plant extracellular vesicles are integrated by a fungal pathogen and inhibit its development. J Exp Bot. 2017;68(20):5485–95. https://doi.org/10.1093/jxb/erx355.
Qiu FS, et al. Rgl-exomiR-7972, a novel plant exosomal microRNA derived from contemporary Rehmanniae Radix, ameliorated lipopolysaccharide-induced acute lung harm and intestine dysbiosis. Biomed Pharmacother. 2023;165:115007. https://doi.org/10.1016/j.biopha.2023.115007.
Zhang M, et al. Edible ginger-derived nanoparticles: a novel therapeutic method for the prevention and remedy of inflammatory bowel illness and colitis-associated most cancers. Biomaterials. 2016;101:321–40. https://doi.org/10.1016/j.biomaterials.2016.06.018.
Tan S, et al. Dandelion-derived vesicles-laden hydrogel dressings able to neutralizing Staphylococcus aureus exotoxins for the care of invasive wounds. J Management Launch. 2024;368:355–71. https://doi.org/10.1016/j.jconrel.2024.02.045.
Cao M, et al. Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma development. J Immunother Most cancers. 2019;7(1):326. https://doi.org/10.1186/s40425-019-0817-4.
Lu Y, et al. Edible pueraria lobata-derived exosome-like nanovesicles ameliorate dextran sulfate sodium-induced colitis related lung irritation by way of modulating macrophage polarization. Biomed Pharmacother. 2024;170:116098. https://doi.org/10.1016/j.biopha.2023.116098.
Hwang JH, et al. Yam-derived exosome-like nanovesicles stimulate osteoblast formation and forestall osteoporosis in mice. J Management Launch. 2023;355:184–98. https://doi.org/10.1016/j.jconrel.2023.01.071.
Zhao Q, et al. An enzyme-based system for extraction of small extracellular vesicles from crops. Sci Rep. 2023;13(1):13931. https://doi.org/10.1038/s41598-023-41224-z.
Rutter BD, Innes RW. Extracellular vesicles remoted from the Leaf Apoplast carry stress-response proteins. Plant Physiol. 2017;173(1):728–41. https://doi.org/10.1104/pp.16.01253.
Liu Y, et al. Characterization of and isolation strategies for plant leaf nanovesicles and small extracellular vesicles. Nanomedicine. 2020;29:102271. https://doi.org/10.1016/j.nano.2020.102271.
O’Leary BM, et al. The infiltration-centrifugation approach for extraction of apoplastic fluid from plant leaves utilizing Phaseolus vulgaris for instance. J Vis Exp. 2014;94. https://doi.org/10.3791/52113.
Du J, et al. Plant-derived phosphocholine facilitates mobile uptake of anti-pulmonary fibrotic HJT-sRNA-m7. Sci China Life Sci. 2019;62(3):309–20. https://doi.org/10.1007/s11427-017-9026-7.
Li X, et al. Natural decoctosome is a novel type of medication. Sci China Life Sci. 2019;62(3):333–48. https://doi.org/10.1007/s11427-018-9508-0.
Fang Z, Liu Okay. Plant-derived extracellular vesicles as oral drug supply carriers. J Management Launch. 2022;350:389–400. https://doi.org/10.1016/j.jconrel.2022.08.046.
Gebeyehu A, et al. Position of Exosomes for supply of chemotherapeutic medication. Crit Rev Ther Drug Provider Syst. 2021;38(5):53–97. https://doi.org/10.1615/CritRevTherDrugCarrierSyst.2021036301.
Li Z, et al. Arrowtail RNA for Ligand Show on Ginger Exosome-like nanovesicles to systemic ship siRNA for Most cancers suppression. Sci Rep. 2018;8(1):14644. https://doi.org/10.1038/s41598-018-32953-7.
Zhang L, et al. Engineering Exosome-Like Nanovesicles Derived from Asparagus cochinchinensis can inhibit the proliferation of Hepatocellular Carcinoma Cells with Higher Security Profile. Int J Nanomed. 2021;16:1575–86. https://doi.org/10.2147/ijn.S293067.
Mu J, et al. Interspecies communication between plant and mouse intestine host cells by way of edible plant derived exosome-like nanoparticles. Mol Nutr Meals Res. 2014;58(7):1561–73. https://doi.org/10.1002/mnfr.201300729.
Théry C, et al. Isolation and characterization of exosomes from cell tradition supernatants and organic fluids. Curr Protoc Cell Biol. 2006;Chap 3:Unit322. https://doi.org/10.1002/0471143030.cb0322s30.
Théry C, et al. Minimal info for research of extracellular vesicles 2018 (MISEV2018): a place assertion of the Worldwide Society for Extracellular Vesicles and replace of the MISEV2014 tips. J Extracell Vesicles. 2018;7(1):1535750. https://doi.org/10.1080/20013078.2018.1535750.
Eivindvik Okay, Sjogren CE. Physicochemical properties of iodixanol. Acta Radiol Suppl. 1995;399:32–8. https://doi.org/10.1177/0284185195036s39904.
Edelstein C, et al. Benefits and limitations of density gradient ultracentrifugation within the fractionation of human serum lipoproteins: position of salts and sucrose. J Lipid Res. 1984;25(6):630–7.
Nordin JZ, et al. Ultrafiltration with size-exclusion liquid chromatography for top yield isolation of extracellular vesicles preserving intact biophysical and useful properties. Nanomedicine. 2015;11(4):879–83. https://doi.org/10.1016/j.nano.2015.01.003.
Haraszti RA, et al. Exosomes produced from 3D cultures of MSCs by tangential Stream Filtration Present Increased Yield and Improved Exercise. Mol Ther. 2018;26(12):2838–47. https://doi.org/10.1016/j.ymthe.2018.09.015.
Zeng X, et al. Characterization and bioassays of extracellular vesicles extracted by tangential movement filtration. Regen Med. 2022;17(3):141–54. https://doi.org/10.2217/rme-2021-0038.
Ansari FJ, et al. Comparability of the effectivity of ultrafiltration, precipitation, and ultracentrifugation strategies for exosome isolation. Biochem Biophys Rep. 2024;38:101668. https://doi.org/10.1016/j.bbrep.2024.101668.
Suharta S, et al. Plant-derived exosome-like nanoparticles: a concise evaluate on its extraction strategies, content material, bioactivities, and potential as useful meals ingredient. J Meals Sci. 2021;86(7):2838–50. https://doi.org/10.1111/1750-3841.15787.
You JY, et al. Isolation of cabbage exosome-like nanovesicles and investigation of their organic actions in human cells. Bioact Mater. 2021;6(12):4321–32. https://doi.org/10.1016/j.bioactmat.2021.04.023.
Böing AN, et al. Single-step isolation of extracellular vesicles by size-exclusion chromatography. J Extracell Vesicles. 2014;3. https://doi.org/10.3402/jev.v3.23430.
Akbar A, et al. Methodologies to isolate and purify medical Grade Extracellular vesicles for medical purposes. Cells. 2022;11(2). https://doi.org/10.3390/cells11020186.
Fortunato D, et al. Selective isolation of extracellular vesicles from minimally processed human plasma as a translational technique for liquid biopsies. Biomark Res. 2022;10(1):57. https://doi.org/10.1186/s40364-022-00404-1.
Chen A, et al. Isolation of Extracellular vesicles from Arabidopsis. Curr Protoc. 2022;2(1):e352. https://doi.org/10.1002/cpz1.352.
Kowal J, et al. Proteomic comparability defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci U S A. 2016;113(8):E968–77. https://doi.org/10.1073/pnas.1521230113.
Rider MA, et al. ExtraPEG: a polyethylene glycol-based Methodology for Enrichment of Extracellular vesicles. Sci Rep. 2016;6:23978. https://doi.org/10.1038/srep23978.
Kalarikkal SP, et al. An economical polyethylene glycol-based methodology for the isolation of useful edible nanoparticles from ginger rhizomes. Sci Rep. 2020;10(1):4456. https://doi.org/10.1038/s41598-020-61358-8.
Webber J, Clayton A. How pure are your vesicles? J Extracell Vesicles. 2013;2. https://doi.org/10.3402/jev.v2i0.19861.
Jang J, et al. Isolation of high-purity and high-stability exosomes from ginseng. Entrance Plant Sci. 2022;13:1064412. https://doi.org/10.3389/fpls.2022.1064412.
Yin L, et al. Characterization of the MicroRNA Profile of Ginger Exosome-like nanoparticles and their anti-inflammatory results in Intestinal Caco-2 cells. J Agric Meals Chem. 2022;70(15):4725–34. https://doi.org/10.1021/acs.jafc.1c07306.
Bai C, et al. Analysis standing and challenges of plant-derived exosome-like nanoparticles. Biomed Pharmacother. 2024;174:116543. https://doi.org/10.1016/j.biopha.2024.116543.
Renaud JP, et al. Cryo-EM in drug discovery: achievements, limitations and prospects. Nat Rev Drug Discov. 2018;17(7):471–92. https://doi.org/10.1038/nrd.2018.77.
Lengthy D, et al. Atomic Drive Microscopy to Characterize Ginger lipid-derived nanoparticles (GLDNP). Bio Protoc. 2021;11(7):e3969. https://doi.org/10.21769/BioProtoc.3969.
Sitar S, et al. Dimension characterization and quantification of exosomes by asymmetrical-flow field-flow fractionation. Anal Chem. 2015;87(18):9225–33. https://doi.org/10.1021/acs.analchem.5b01636.
Fortunato D, et al. Alternatives and pitfalls of fluorescent labeling methodologies for Extracellular Vesicle profiling on high-resolution single-particle platforms. Int J Mol Sci. 2021;22(19). https://doi.org/10.3390/ijms221910510.
Cao Y, et al. Morinda Officinalis-derived extracellular vesicle-like particles: anti-osteoporosis impact by regulating MAPK signaling pathway. Phytomedicine. 2024;129:155628. https://doi.org/10.1016/j.phymed.2024.155628.
Teng Y, et al. Plant-derived exosomal MicroRNAs form the intestine microbiota. Cell Host Microbe. 2018;24(5):637–52.e8. https://doi.org/10.1016/j.chom.2018.10.001.
Ramirez MI, et al. Technical challenges of working with extracellular vesicles. Nanoscale. 2018;10(3):881–906. https://doi.org/10.1039/c7nr08360b.
Zhang M, et al. Plant derived edible nanoparticles as a brand new therapeutic method towards illnesses. Tissue Limitations. 2016;4(2):e1134415. https://doi.org/10.1080/21688370.2015.1134415.
Zeng L, et al. Aloe derived nanovesicle as a useful provider for indocyanine inexperienced encapsulation and phototherapy. J Nanobiotechnol. 2021;19(1):439. https://doi.org/10.1186/s12951-021-01195-7.
Raimondo S, et al. Citrus limon-derived nanovesicles inhibit most cancers cell proliferation and suppress CML xenograft development by inducing TRAIL-mediated cell demise. Oncotarget. 2015;6(23):19514–27. https://doi.org/10.18632/oncotarget.4004.
Birnbaum F, et al. [Intracameral application of corticosteroids for treating severe endothelial rejection after penetrating keratoplasty]. Ophthalmologe. 2007;104(9):813–6. https://doi.org/10.1007/s00347-007-1615-9.
Cai Q, et al. Crops ship small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes. Science. 2018;360(6393):1126–9. https://doi.org/10.1126/science.aar4142.
Huang Y, et al. Efficient strategies for isolation and purification of extracellular vesicles from crops. J Integr Plant Biol. 2021;63(12):2020–30. https://doi.org/10.1111/jipb.13181.
Pinedo M, et al. A name for Rigor and standardization in plant extracellular vesicle analysis. J Extracell Vesicles. 2021;10(6):e12048. https://doi.org/10.1002/jev2.12048.
Ren J, et al. From buildings to features: insights into exosomes as promising drug supply autos. Biomater Sci. 2016;4(6):910–21. https://doi.org/10.1039/c5bm00583c.
Yi Q, et al. Present understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment. Pharmacol Res. 2023;190:106733. https://doi.org/10.1016/j.phrs.2023.106733.
Kim J, et al. Anti-glioma impact of ginseng-derived exosomes-like nanoparticles by lively blood-brain-barrier penetration and tumor microenvironment modulation. J Nanobiotechnol. 2023;21(1):253. https://doi.org/10.1186/s12951-023-02006-x.
Li S, et al. Panax notoginseng: derived exosome-like nanoparticles attenuate ischemia reperfusion harm by way of altering microglia polarization. J Nanobiotechnol. 2023;21(1):416. https://doi.org/10.1186/s12951-023-02161-1.
Sundaram Okay, et al. Plant-derived exosomal nanoparticles inhibit pathogenicity of Porphyromonas gingivalis. iScience. 2019;21:308–27. https://doi.org/10.1016/j.isci.2019.10.032.
Ju S, et al. Grape exosome-like nanoparticles induce intestinal stem cells and defend mice from DSS-induced colitis. Mol Ther. 2013;21(7):1345–57. https://doi.org/10.1038/mt.2013.64.
Zhuang X, et al. Ginger-derived nanoparticles defend towards alcohol-induced liver harm. J Extracell Vesicles. 2015;4:28713. https://doi.org/10.3402/jev.v4.28713.
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and performance. Cell. 2004;116(2):281–97. https://doi.org/10.1016/s0092-8674(04)00045-5.
Xiao J, et al. Identification of exosome-like nanoparticle-derived microRNAs from 11 edible vegetables and fruit. PeerJ. 2018;6:e5186. https://doi.org/10.7717/peerj.5186.
Isaac R, et al. Exosomes as mediators of intercellular crosstalk in metabolism. Cell Metab. 2021;33(9):1744–62. https://doi.org/10.1016/j.cmet.2021.08.006.
Yan L, et al. Ginger exosome-like nanoparticle-derived miRNA therapeutics: a strategic inhibitor of intestinal irritation. J Adv Res. 2024. https://doi.org/10.1016/j.jare.2024.04.001.
Zhu H, et al. Figuring out the potential of miRNAs in Houttuynia cordata-derived Exosome-Like nanoparticles towards respiratory RNA viruses. Int J Nanomed. 2023;18:5983–6000. https://doi.org/10.2147/ijn.S425173.
Chin AR, et al. Cross-kingdom inhibition of breast most cancers development by plant miR159. Cell Res. 2016;26(2):217–28. https://doi.org/10.1038/cr.2016.13.
Zhao Q, et al. Rhizoma Drynariae-derived nanovesicles reverse osteoporosis by potentiating osteogenic differentiation of human bone marrow mesenchymal stem cells by way of concentrating on ERα signaling. Acta Pharm Sin B. 2024;14(5):2210–27. https://doi.org/10.1016/j.apsb.2024.02.005.
Woith E, et al. Plant Extracellular vesicles and nanovesicles: concentrate on secondary metabolites, proteins and lipids with views on their potential and sources. Int J Mol Sci. 2021;22(7). https://doi.org/10.3390/ijms22073719.
Date AA, et al. Nanoparticles for oral supply: design, analysis and state-of-the-art. J Management Launch. 2016;240:504–26. https://doi.org/10.1016/j.jconrel.2016.06.016.
Ensign LM, et al. Oral drug supply with polymeric nanoparticles: the gastrointestinal mucus obstacles. Adv Drug Deliv Rev. 2012;64(6):557–70. https://doi.org/10.1016/j.addr.2011.12.009.
Gao Q, et al. Pure lipid nanoparticles extracted from Morus nigra L. leaves for focused remedy of hepatocellular carcinoma by way of the oral route. J Nanobiotechnol. 2024;22(1):4. https://doi.org/10.1186/s12951-023-02286-3.
Yang M, et al. An environment friendly methodology to isolate lemon derived extracellular vesicles for gastric most cancers remedy. J Nanobiotechnol. 2020;18(1):100. https://doi.org/10.1186/s12951-020-00656-9.
Xin T, et al. Tendencies in herbgenomics. Sci China Life Sci. 2019;62(3):288–308. https://doi.org/10.1007/s11427-018-9352-7.
Zheng Y, et al. Protecting impact of Contemporary/Dry dandelion extracts on APAP-Overdose-Induced Acute Liver Harm. Chin J Integr Med. 2022;28(8):683–92. https://doi.org/10.1007/s11655-021-3295-8.
Zhang W, et al. Comparability of the antioxidant actions and polysaccharide characterization of Contemporary and Dry Dendrobium officinale Kimura et Migo. Molecules. 2022;27(19). https://doi.org/10.3390/molecules27196654.
Gu JF, et al. Comparability on hypoglycemic and antioxidant actions of the contemporary and dried Portulaca oleracea L. in insulin-resistant HepG2 cells and streptozotocin-induced C57BL/6J diabetic mice. J Ethnopharmacol. 2015;161:214–23. https://doi.org/10.1016/j.jep.2014.12.002.
Vidal-Gallardo A, et al. The position of intestine microbiome within the Pathogenesis and the remedy of Inflammatory Bowel illnesses. Cureus. 2024;16(2):e54569. https://doi.org/10.7759/cureus.54569.
Medzhitov R. Origin and physiological roles of irritation. Nature. 2008;454(7203):428–35. https://doi.org/10.1038/nature07201.
Ito Y, et al. Uptake of MicroRNAs from Exosome-Like nanovesicles of Edible Plant Juice by Rat Enterocytes. Int J Mol Sci. 2021;22(7). https://doi.org/10.3390/ijms22073749.
Liu C, et al. Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis remedy. J Nanobiotechnol. 2022;20(1):206. https://doi.org/10.1186/s12951-022-01421-w.
Gao C, et al. Turmeric-derived nanovesicles as novel nanobiologics for focused remedy of ulcerative colitis. Theranostics. 2022;12(12):5596–614. https://doi.org/10.7150/thno.73650.
Chen X, et al. Exosome-like nanoparticles from Ginger rhizomes Inhibited NLRP3 inflammasome activation. Mol Pharm. 2019;16(6):2690–9. https://doi.org/10.1021/acs.molpharmaceut.9b00246.
Liu B, et al. Protecting position of Shiitake Mushroom-Derived Exosome-Like nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Harm in mice. Vitamins. 2020;12(2). https://doi.org/10.3390/nu12020477.
Sriwastva MK, et al. Exosome-like nanoparticles from Mulberry bark stop DSS-induced colitis by way of the AhR/COPS8 pathway. EMBO Rep. 2022;23(3):e53365. https://doi.org/10.15252/embr.202153365.
Wu J, et al. Edible Pueraria lobata-derived exosomes promote M2 macrophage polarization. Molecules. 2022;27(23). https://doi.org/10.3390/molecules27238184.
Chota A, et al. Potential remedy of breast and Lung Most cancers utilizing Dicoma anomala, an African Medicinal Plant. Molecules. 2020;25(19). https://doi.org/10.3390/molecules25194435.
Liang J, et al. Sphingosine-1-phosphate hyperlinks persistent STAT3 activation, continual intestinal irritation, and growth of colitis-associated most cancers. Most cancers Cell. 2013;23(1):107–20. https://doi.org/10.1016/j.ccr.2012.11.013.
Chen Q, et al. Pure exosome-like nanovesicles from edible tea flowers suppress metastatic breast most cancers by way of ROS era and microbiota modulation. Acta Pharm Sin B. 2022;12(2):907–23. https://doi.org/10.1016/j.apsb.2021.08.016.
Han X, et al. Ginseng-derived nanoparticles potentiate immune checkpoint antibody efficacy by reprogramming the chilly tumor microenvironment. Mol Ther. 2022;30(1):327–40. https://doi.org/10.1016/j.ymthe.2021.08.028.
Lv Y, et al. Ginseng-derived nanoparticles reprogram macrophages to control arginase-1 launch for ameliorating T cell exhaustion in tumor microenvironment. J Exp Clin Most cancers Res. 2023;42(1):322. https://doi.org/10.1186/s13046-023-02888-7.
Kim Okay, et al. Anti-metastatic results of Plant Sap-Derived Extracellular vesicles in a 3D Microfluidic Most cancers Metastasis Mannequin. J Funct Biomater. 2020;11(3). https://doi.org/10.3390/jfb11030049.
Yan G, et al. Brucea Javanica derived exosome-like nanovesicles ship miRNAs for most cancers remedy. J Management Launch. 2024;367:425–40. https://doi.org/10.1016/j.jconrel.2024.01.060.
Narauskaitė D, et al. Extracellular vesicles in pores and skin Wound Therapeutic. Prescription drugs (Basel). 2021;14(8). https://doi.org/10.3390/ph14080811.
Yang S, et al. Ginseng-derived nanoparticles induce pores and skin cell proliferation and promote wound therapeutic. J Ginseng Res. 2023;47(1):133–43. https://doi.org/10.1016/j.jgr.2022.07.005.
Kim MK, et al. The antioxidant impact of small extracellular vesicles derived from Aloe vera peels for Wound Therapeutic. Tissue Eng Regen Med. 2021;18(4):561–71. https://doi.org/10.1007/s13770-021-00367-8.
Kim M, Park JH. Isolation of Aloe saponaria-derived extracellular vesicles and investigation of their potential for continual Wound Therapeutic. Pharmaceutics. 2022;14(9). https://doi.org/10.3390/pharmaceutics14091905.
Şahin F, et al. In Vitro Wound Therapeutic exercise of wheat-derived nanovesicles. Appl Biochem Biotechnol. 2019;188(2):381–94. https://doi.org/10.1007/s12010-018-2913-1.
Fang F, et al. The position and purposes of extracellular vesicles in osteoporosis. Bone Res. 2024;12(1):4. https://doi.org/10.1038/s41413-023-00313-5.
Bijlsma AY, et al. Chronology of age-related illness definitions: osteoporosis and sarcopenia. Ageing Res Rev. 2012;11(2):320–4. https://doi.org/10.1016/j.arr.2012.01.001.
Zhan W, et al. Pueraria lobata-derived exosome-like nanovesicles alleviate osteoporosis by enhacning autophagy. J Management Launch. 2023;364:644–53. https://doi.org/10.1016/j.jconrel.2023.11.020.
Park YS, et al. Plum-Derived Exosome-like nanovesicles induce differentiation of osteoblasts and discount of Osteoclast activation. Vitamins. 2023;15(9). https://doi.org/10.3390/nu15092107.
Sim Y, et al. The Impact of Apple-Derived nanovesicles on the osteoblastogenesis of Osteoblastic MC3T3-E1 cells. J Med Meals. 2023;26(1):49–58. https://doi.org/10.1089/jmf.2022.K.0094.
Lee R, et al. Anti-melanogenic results of extracellular vesicles derived from plant leaves and stems in mouse melanoma cells and human wholesome pores and skin. J Extracell Vesicles. 2020;9(1):1703480. https://doi.org/10.1080/20013078.2019.1703480.
Cho EG et al. Panax ginseng-Derived Extracellular Vesicles Facilitate Anti-Senescence Results in Human Pores and skin Cells: An Eco-Pleasant and Sustainable Strategy to Use Ginseng Substances, Cells 10(3) (2021). https://doi.org/10.3390/cells10030486
Baldini N, et al. Exosome-like nanovesicles remoted from Citrus limon L. Exert Antioxidative Impact. Curr Pharm Biotechnol. 2018;19(11):877–85. https://doi.org/10.2174/1389201019666181017115755.
Mahdipour E. Beta vulgaris juice comprises biologically lively exosome-like nanoparticles. Tissue Cell. 2022;76:101800. https://doi.org/10.1016/j.tice.2022.101800.
Perut F, et al. Strawberry-Derived Exosome-Like nanoparticles stop oxidative stress in human mesenchymal stromal cells. Biomolecules. 2021;11(1). https://doi.org/10.3390/biom11010087.
Zhang M, et al. Edible ginger-derived Nano-lipids loaded with doxorubicin as a Novel Drug-delivery Method for Colon most cancers remedy. Mol Ther. 2016;24(10):1783–96. https://doi.org/10.1038/mt.2016.159.
Wang B, et al. Focused drug supply to intestinal macrophages by bioactive nanovesicles launched from grapefruit. Mol Ther. 2014;22(3):522–34. https://doi.org/10.1038/mt.2013.190.
Xiao Q, et al. Lemon-Derived Extracellular vesicles Nanodrugs allow to effectively overcome Most cancers Multidrug Resistance by endocytosis-triggered Power Dissipation and Power Manufacturing discount. Adv Sci (Weinh). 2022;9(20):e2105274. https://doi.org/10.1002/advs.202105274.
Cao Y, et al. A complete evaluation of the Bencao (natural) small RNA Atlas reveals novel RNA therapeutics for treating human illnesses. Sci China Life Sci. 2023;66(10):2380–98. https://doi.org/10.1007/s11427-022-2181-6.
Zhang YL, et al. Conventional Chinese language Medication Formulae QY305 decreasing cutaneous hostile response and diarrhea by its nanostructure. Adv Sci (Weinh). 2024;11(5):e2306140. https://doi.org/10.1002/advs.202306140.
Zarovni N, et al. Built-in isolation and quantitative evaluation of exosome shuttled proteins and nucleic acids utilizing immunocapture approaches. Strategies. 2015;87:46–58. https://doi.org/10.1016/j.ymeth.2015.05.028.
Konoshenko MY, et al. Isolation of Extracellular vesicles: Common methodologies and newest developments. Biomed Res Int. 2018;2018:8545347. https://doi.org/10.1155/2018/8545347.
Sidhom Okay, et al. A evaluate of Exosomal isolation strategies: is measurement Exclusion Chromatography the best choice? Int J Mol Sci. 2020;21(18). https://doi.org/10.3390/ijms21186466.
Zhu MZ, et al. Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis by way of facilitating double-positive CD4(+)CD8(+)T cells enlargement. J Nanobiotechnol. 2023;21(1):309. https://doi.org/10.1186/s12951-023-02065-0.
Kim WS et al. Immunological Results of Aster yomena Callus-Derived Extracellular Vesicles as Potential Therapeutic Brokers towards Allergic Bronchial asthma, Cells 11(18) (2022). https://doi.org/10.3390/cells11182805
Kumar A, et al. Ginger nanoparticles mediated induction of Foxa2 prevents high-fat diet-induced insulin resistance. Theranostics. 2022;12(3):1388–403. https://doi.org/10.7150/thno.62514.
Ramírez O, et al. Aloe vera peel-derived nanovesicles show anti-inflammatory properties and forestall myofibroblast differentiation. Phytomedicine. 2024;122:155108. https://doi.org/10.1016/j.phymed.2023.155108.
Sundaram Okay, et al. Garlic exosome-like nanoparticles reverse high-fat weight loss program induced weight problems by way of the intestine/mind axis. Theranostics. 2022;12(3):1220–46. https://doi.org/10.7150/thno.65427.
Zhang M, et al. Oral administration of ginger-derived nanolipids loaded with siRNA as a novel method for environment friendly siRNA drug supply to deal with ulcerative colitis. Nanomed (Lond). 2017;12(16):1927–43. https://doi.org/10.2217/nnm-2017-0196.
Wang X, et al. Oral gavage of Ginger nanoparticle-derived lipid vectors carrying Dmt1 siRNA blunts Iron Loading in Murine Hereditary Hemochromatosis. Mol Ther. 2019;27(3):493–506. https://doi.org/10.1016/j.ymthe.2019.01.003.